I remember my grandmother saying that $2 bills were considered bad luck,
but I don't remember that it was based on anything.  I also remember
from my youth a saying  "queer as a $2 bill."  I have a vague idea in my
head that a general reluctance to use them (because of this
superstition) explains why the feds have been unsuccessful in
circulating them.

Maybe it's regional?  I was born/brought up in NH.

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